In this article, Julia Gottwald, Sanne de Wit, and colleagues investigated performance of teenagers with obsessive-compulsive disorder (OCD) on critical cognitive domains for daily functioning and academic success, including goal-directed behavioral control, cognitive flexibility, learning, and memory. Patients demonstrated a significant learning and memory impairment compared to healthy control subjects, as well as impairments in goal-directed goal and cognitive plasticity. These results add to our understanding of juvenile OCD.
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Gottwald, J., De Wit, S., Apergis-Schoute, A., Morein-Zamir, S., Kaser, M., Cormack, F., . . . Sahakian, B. (2018). Impaired cognitive plasticity and goal-directed control in adolescent obsessive–compulsive disorder. Psychological Medicine, 1-9.